CBD and Sickle Cell Anemia

Peer-reviewed studies into the potential effects of Cannabidiol and Sickle cell anemia

On this page, CBD and Sickle Cell Anemia, you will find research pertaining to the use of Cannabidiol and Cannabinoids and its possible effects on Sickle cell anemia. The information below is not meant to influence your opinion, but rather give you access to a wealth of scientific literature in an attempt to make and educated and informed choice. Click Here to see all of the conditions that have been researched alongside CBD and Sickle Cell Anemia.

Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids

From the abstract:

Sickle cell disease causes severe pain. We examined pain-related behaviors, correlative neurochemical changes, and analgesic effects of morphine and cannabinoids in transgenic mice expressing human sickle hemoglobin (HbS)… We show that mice expressing HbS exhibit characteristics of pain observed in sickle cell disease patients, and neurochemical changes suggestive of nociceptor and glial activation. Importantly, cannabinoids attenuate pain in mice expressing HbS.

Cannabis use in sickle cell disease: a questionnaire study.

From the abstract:

Cannabinoids are increasingly being considered for the management of various painful conditions, and could be considered as an option for treating acute pain in sickle cell disease (SCD). The objective of this study was to determine the extent of use of cannabis in the community for pain and other symptom relief, and its side effects during self-administration in patients with SCD… We conclude that research in the use of cannabinoids for pain relief in SCD would be both important and acceptable to adult patients.