CBD and Endocrine Disorders

Peer-reviewed studies into the potential effects of Cannabidiol and endocrine disorders

On this page, CBD and Endocrine Disorders, you will find research pertaining to the use of Cannabidiol and Cannabinoids and its possible effects on Endocrine Disorders. The information below is not meant to influence your opinion, but rather give you access to a wealth of scientific literature in an attempt to make and educated and informed choice. Click Here to see all of the conditions that have been researched alongside CBD and Endocrine Disorders. If you have any questions pertaining to the research, please email us at info@hempicated.com.

Endocannabinoid System Participates in Neuroendocrine Conrol of Homeostasis

From the abstract:

The endocannabinoid system is a new intercellular system that modulates several neuroendocrine actions. . Endocannabinoids (eCB) are released as retrograde messengers by many neurons, including hypothalamic magnocellular neurons and cannabinoid receptors are localized within these neurons, as well as in the anterior and posterior pituitary lobes, suggesting an eCB role in the production and release of [oxytocin] and [vasopressin] 

*The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance*

From the abstract:

CB1 receptor is the most abundant G protein-coupled receptor expressed in the brain. CB1 receptor is expressed in the hypothalamus and the pituitary gland, and its activation is known to modulate all the endocrine hypothalamic-peripheral endocrine axes. An Increasing amount of data highlights the role of the system in the stress response by influencing the hypothalamic-pituitary-adrenal axis and the control of reproduction by modifying gonadotropin release, fetility, and sexual behavior.

Endocannabinoids in endocrine related tumours 

From the abstract:

Indeed, recent evidence indicates that endocannabinoids influence the intracellular events controlling the proliferation of numerous types of endocrine and related cancer cells, thereby leading to both in vitro and in vivo antitumour effects. In particular, they are able to inhibit cell growth, invasion and metastasis of thyroid, brest and prostate tumours.

Role of the endocannabinoid system in food intake, energy homeostasis and regulation of the endocrine pancreas  

From the abstract:

…activation of cannabinoid receptors expressed by islet scells can stimulate insulin secretion, which is obviously beneficial under conditions of impaired glucose tolerance or type 2 diabetes. We propose that under normal physiological conditions cannabinoid signalling in the endocrine pancreas is a bona fide mechanism of regulating insulin secretion to maintain blood glucose levels…

The role of the endocannabinoid system in the neuroendocrine regulation of energy balance

From the abstract:

The [endocannabinoid system] has been found to interact with peripheral signals, like leptin, insulin, ghrelin and satiety hormones and the resulting effects on both central and peripheral mechanisms affecting energy balance and adiposity will be described… Thus, a perspective on new promising strategies to selectively target the [endocannabinoid system} in the context of energy balance regulation is given.