CBD and Acne

Peer-reviewed studies into the potential effects of Cannabidiol and Acne

On this page, CBD and Acne, you will find research pertaining to the use of Cannabidiol and Cannabinoids and its possible effects on Acne. The information below is not meant to influence your opinion, but rather give you access to a wealth of scientific literature in an attempt to make and educated and informed choice. Click Here to see all of the conditions that have been researched alongside CBD and Acne. If you have any questions pertaining to the research, please email us at info@hempicated.com.

Cannabidiol as a Treatment for acne?

From the article:

Acne involves the overproduction of sebum, a lipid excreted by the sebaceous glands… [CBD] does not stimulate but inhibits lipid synthesis, especially if the lipid synthesis was previously upregulated, as for the example in acne

The safety and efficacy of 3{03c6ed9c7292793a5635106886a6facae0686a7e7bfbe6c29280aa83fc7d030a} cannabis seeds extract cream for reduction of uman cheek skin sebum and erythema content

From the abstract:

Escalated sebum fabrication is seen with an unattractive look and adds to the growth of acne… measurements demonstrated that skin sebum and erythema content of base plus 3{03c6ed9c7292793a5635106886a6facae0686a7e7bfbe6c29280aa83fc7d030a} cannabis seeds extract treated side showed significant decrease (p<0.05) compared with base treated side… Its improved efficacy could be suggested for treament of acne vulgaris, seborrhea, papules, and pustules to get attractive facial appearance.


Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

From the abstract:

Collectively, our findings suggest that, due to the combined lipostatic, antiproliferative, and antiinflammatory effects, CBD has potential as a promising therapeutic agent for the treatment of ace vulgaris.

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

From the abstract:

Recent studies have intriguingly suggested the existence of a functiona [endocannabinoid system] in the skin and implicated it in various biological processes… It seems that the main physiological function of the cutaneous ECS is to constitutively control the proper and well-balanced proliferation, differentiation and survival, as well as immune competence and/or tolerance, of skin cells.

Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling

From the abstract:

Here, we provide the first evidence that SZ95 sebocytes express CB2 but not CB1… Because cells were ‘silenced’ CB2 exhibited significantly suppressed basal lipid productiona… CB2 antagonists or agonists therefore deserve to be explored in the management of skin disorders characterized by sebaceous gland dysfunctions.

Endocannabinoid signaling and epidermal differentiation

From the abstract:

we shall discuss some aspects of the molecular regulation by endocannabinoids of proliferation and terminal differentiation… showing that [endocannabinoid system] is finely regulated by, and can interfere with, the differentiation program. In addition, we shall review evidence demonstrating that disruption of this fine regulation might cause different skin diseases… making ECS an attractive target for therapeutic intervention.

Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment

From the abstract:

based on their remarkable anti-inflammatory actions, phytocannabinoids could be efficient, yet safe novel tools in the management of cutaneous inflammations.